Can Fruit Flies Have Autism?
In a recent study, researchers looked at the effects of ASD gene variants on fruit flies. They found that some flies showed changes in their behavior during social interactions, including repetitive behavior. The researchers also observed changes in flies’ gene expression. These changes are similar to those seen in people with ASD.
The results showed that the genetic changes reduced the flies’ eye size and wing size, and reduced their courtship and grooming behaviors. In addition, scientists discovered that 13 unrelated individuals carry rare variants of a gene that controls the chemical messenger glycine in the brain. These variants are linked to autism and other neurodevelopmental disorders.
Although it has been hypothesized that humans share many genes with fruit flies, scientists do not know whether fruit flies can have autism. The species has many genes in common with humans that are necessary for normal cognitive functions. Its ability to exhibit complex behaviors is similar to that of humans, and this makes it a good model for autism research. Furthermore, fruit flies are easy to maintain and reproduce in large numbers. This gives them an advantage over mice and rats.
Scientists are now using fruit flies to investigate autism. The flies’ olfactory system, which controls their response to different kinds of sounds and odors, is similar to the one in humans. Researchers say this may give us an idea of how autism is caused by a malfunctioning of brain circuits.