Can Fleas Become Immune to Frontline?

Although there is no definitive answer to the question of “Can fleas become immune to Frontline?”, some scientific evidence suggests that some fleas may develop resistance to the active ingredients of Frontline Plus. This can make the medication less effective than it should be. In this case, you should consider switching to an alternative flea and tick prevention product.

One common reason for fleas to become resistant to a pesticide is human error. Veterinarians say that fleas may become resistant to a particular topical treatment due to a combination of factors. For example, some fleas have developed resistance to a particular insecticide because it has been used on their host for an extended period of time.

Other potential reasons for flea resistance include indoor breeding. Some treatments contain insecticides with multiple modes of action, such as fipronil and pyriproxyfen. This may delay the development of resistance. In addition, some treatments contain a synergistic effect between insecticides with different modes of action.

Frontline Plus is a topical treatment that kills fleas and ticks. It is given to dogs once per month. It contains the active ingredient fipronil, which is safe for most dogs. It is manufactured by Merial.

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