Can Rats Take Aspirin?
WouterThis study was designed to determine whether or not rats can take aspirin. Rats were divided into five groups. One group received a placebo (powder) and four other groups were given aspirin tablets. The aspirin tablets were ground up and diluted in water, and given orally once a day for 30 days. The rats were then sacrificed and the livers were examined for gross and histological changes.
When rats were administered aspirin, their body weight increased significantly less than that of the control group. The study also showed that aspirin treatment induced an increase in basophilia and sinusoidal congestion. In addition, rats were shown to have decreased sensitivity to aspirin when given at a low dose.
Despite the risks of taking aspirin, some studies suggest that it can help prevent certain cancers. Aspirin, which inhibits COX activity, is a safe choice for this purpose. It also has a protective effect against certain types of gastrointestinal tumors. In fact, it is the only drug that combines cardiovascular protection with the prevention of certain types of cancer.
It is safe to give rats aspirin as long as they follow proper dosage guidelines. However, there are some precautions to be kept in mind. Aspirin is highly effective for treating most types of pain, and is effective in extending the bleeding time. However, aspirin can be toxic if it is taken in large amounts, and is unlikely to be suitable for pregnant or lactating rats. Besides, aspirin interferes with ovulation in female rats.
